Politicians condemned the attack, which follows a string of arson attacks on synagogues and other Jewish sites in the city. Prime Minister Keir Starmer said "attacks on our Jewish community are attacks on Britain".
The security organisation Shomrim said a suspect "was seen running along Golders Green Road armed with a knife and attempting to stab Jewish members of the public" on Wednesday morning.
It said the suspect was detained by Shomrim members before being arrested by police, who used a stun gun on the man.
The Metropolitan Police said the victims, a man in his 30s and one in his 70s, were hospitalised in stable condition.
The force said the suspect also tried to stab police officers but none were injured.
Counterterrorism detectives are leading the investigation, but it has not been declared an act of terrorism.
London Mayor Sadiq Khan said "London's Jewish community have been the target of a series of shocking anti-Semitic attacks".
"There must be absolutely no place for anti-Semitism in society," he said.
The incident follows arson attacks in recent weeks targeting Jewish sites in London, including a charity's ambulances in Golders Green and a synagogue a few kilometres away.
Counterterrorism officers are investigating whether the arson attacks were the work of Iranian proxies.
No one was injured in the arson incidents, which all happened within a few miles of each other.
Several people, ranging in age from teens to people in their 40s, have been arrested and charged.
Britain's Jewish community is long-established but tiny as a percentage of the population, numbering about 300,000.
The northwest London suburb of Golders Green is one of its epicenters, home to kosher restaurants, multiple Jewish schools and several dozen synagogues, as well as large Asian and Middle Eastern communities.
Britain's chief rabbi has said that UK Jews are facing a campaign of violence and intimidation.
The number of anti-Semitic incidents reported across the UK has soared since the October 7, 2023, attack by Hamas on Israel and the subsequent Gaza war, according to the Community Security Trust.
The group recorded 3700 incidents in 2025, up from 1662 in 2022.
In October 2025, an attacker drove his car into people gathered outside a Manchester synagogue on Yom Kippur and stabbed one person to death.
Another person died during the attack after being inadvertently shot by police.
